7.What is lactoferrin? Lactoferrin (LF), also known as lactotransferrin (LTF), is a multifunctional protein of the transferrin family.
Lactoferrin is a globular glycoprotein with a molecular mass of about 80 kDa that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin is also present in secondary granules of PMN and is secreted by some acinar cells. Lactoferrin can be purified from milk or produced recombinantly.
Human colostrum ("first milk") has the highest concentration, followed by human milk, then cow milk (150 mg/L).
Lactoferrin is one of the components of the immune system of the body; it has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses. In particular, lactoferrin provides antibacterial activity to human infants.
Lactoferrin interacts with DNA and RNA, polysaccharides and heparin, and shows some of its biological functions in complexes with these ligands.
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Lactoferrin is the composition material of the innate immune system proteins . In addition to the main functions of combining and transporting the iron , Lactoferrin also has the functions and attributes of antibacterial iron, antivirus, resistance to parasites, catalysis, cancer prevention and fighting against cancer, allergy and radiation protection.
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