NutraMax Inc.- mulberry root extract (Anthocyandins 5%-25%)

NutraMax mulberry root extract

Mulberry fruit (Morus Lhou Koidz.), a rich source of the major anthocyanin, cyanidin 3glucoside (C3G), has traditionally been used for the treatment of inflammatory conditions including rheumatic arthritis. In this study, we evaluated the efficacy of orally administrated methanolic mulberry fruit extract (ME) in carrageenan-induced arthritic rats, based on previously observed in vitro antioxidant and anti-inflammatory activities. A significant attenuation of hind paw inflammation characterized by fluid accumulation, uric acid production, and rheumatoid factors induced by carrageenan was observed following the intake of both ME (50 mg/kg of body weight) and C3G (10 mg/kg of body weight). Moreover, alterations in hematological parameters such as serum triglyceride, high-density lipoprotein-cholesterol, and atherogenic index following carrageenan administration were partially reversed by the administration of ME. It is concluded that dietary mulberry fruit extracts elicited protection against carrageenan-induced inflammation.

1-Deoxynojirimycin(DNJ) is a kind of alkaloid present in Mulberry leaves and root bark. DNJ is naturally occurs in in other plants and microbes. We extract the DNJ from leaf of Morus alba L.Research shows that when DNJ entered the body, it can inhibit the decomposition of starch and sugar by sucrase, maltase, α-glucosidase, α-amylase enzyme, thus blocking the body's absorption of sugar, and inhibit the increase of glucose without diet change. In addition, DNJ can inhibit the glucose modification process of HIV membrane glycoprotein. Meanwhile, the accumulation of immature glycoproteins may inhibit the cell fusion and the binding between virus and host cell receptor, and the formation of cell body harmony to inhibit the the replication of MoLV so as to inhibit the viral activity.

ÔÔ What is the Function of mulberry root extract in NutraMax ?

NutraMax mulberry root extract

Mulberry leaves, spades shaped, are the preferred feedstock for silkworms, and are also cut for food for livestock (cattle, goats, etc.) in areas where dry seasons restrict the availability of ground vegetation. The leaves were also long used for medicinal purposes.

In traditional Chinese medicine, the mulberry leaf extract are considered to be of sweet, bitter and cold properties, which are associated with the liver and lung meridians, and functions to clear lung heat (to manifest as a fever, headache,sore throat or cough) and clear fire in the liver. They are also used to stop bleeding, especially in patients who are vomiting blood.

The mulberry leaf extract helps restore the vascular reactivity of diabetic rats. Free radical-induced vascular dysfunction plays a key role in the pathogenesis of vascular disease found in chronic diabetic patients.The mulberry leaf extract had antihyperglycemic, antioxidant and antiglycation effects in chronic diabetic rats, which may suggest its use as food supplement for diabetics. Mulberry leaf extract has been studied to process potent antisnake venom property, especially against the local and systemic effects of Daboia russelii venom