The urtica extract is extracted from dried whole grass of Urtica cannabina L. and Urtica angustifolia Fisch.ex Hornem. mainly contain flavonoids, lignans, steroids, lipids, organic acids, proteins, tannins, chlorophyll, alkaloids and chlorophyll. Polysaccharides and other components. It has antirheumatic, hypoglycemic, and benign prostatic hypertrophy.
The urtica extract contains many kinds of active ingredients as follow:
1. chemical constituents of nettle
The compounds isolated and identified from 95% ethanol extract of Urtica root were cis-3-O-beta-glucose methyl-4-[bis(3-methoxy-4-hydroxyphenyl) methyl] butyrolactone, trans-3-O-beta-glucose methyl-4-[bis(3-methoxy-4-hydroxyphenyl) methyl] butyrolactone, trans-3-dimethoxyphenyl] methyl] butyrolactone O-beta-glucose methyl-4-[3-methoxy-4-hydroxyphenyl-3,4-dimethoxyphenyl] methyl] butyrolactone, alpha-aromatic resin alcohol, beta-aromatic resin alcohol, oleanolic acid, bis (5-formylfuryl) ether, 5-hydroxymethyl furfural, 4-hydroxybenzoic acid, scopolamine, scopolamine glycoside, carotene, beta-sitosterol.
Palmitic acid, stigmasterol, alpha-spinosterol, cholesterol-5,22-diene-3-beta-ol and stigmasterol-3-O-beta-D-glucoside were isolated and identified from the alcohol extract of Urtica root.
Chemical constituents of nettle
Thirty-four compounds were isolated and identified from 95% ethanol extract of the aerial part of Urtica latifolia, which were 5 monoterpene glycosides: Roseoside II, (6R, 9R) - 3 - O - A - ionol - beta - D - glucoside, (6S, 9R) - 3 - O - A - ionol - beta - D - glucoside, (6R, 9R) - 3 - O - A - ionol - beta - D - glucoside. 1_2-beta-D-glucoside, (6S, 9R) -3-oxy-a-ionol-beta-D-glucoside (1_2) -beta-D-glucoside, of which the latter three are new compounds; five flavonoid glycosides: apigenin-6, 8-di-C-beta-D-pyranoside, luteolin-7-O-neohesperidin, luteolin-7-O-O-glucoside, luteolin-7-O-beta-D-pyranoside, 5-methoxy-glucoside Luteolin-7-O-beta-D-glucopyranoside, rutin; 2 lignans: (+) turpentine-4-O-alpha-L-rhamnosyl (1_2) -beta-D-glucopyranoside (new compound), isolaricin-9-O-beta-D-glucopyranoside; 2 alkaloids: 2, 3, 4, 9-tetrahydro-1H-pyridine [3, 4-b] indole-3, carboxylic acid 4,9-tetrahydro-1-methyl-pyridine [3,4-b] indole-3-carboxylic acid [3,4-b] indole-3-carboxylic acid; 10 triterpenoidand sterosteroids: 5 alpha, 6 beta-dihydroxy-carotenoside, 2 alpha, 3 alpha, 3 alpha, 19 alpha-trihydroxy-12-olefin-28-ursuric acid, 2 alpha, 3 beta-dihydroxy-oleoleoleoleoleoleoleoleolene, stigmaster-4-4-4-4-4-enoenone-3-3-ketone, 2 alpha, 3 alpha, 3 alpha, 3 alpha, 3 alpha, 19 alpha, 19 alpha, 19 alpha-trihydroxy-triAlcohol, Lupineol, carotene, sitosterol; 1 coumarin and 1 phenylpropanoid: scopolamine, p-hydroxycinnamic acid; 2 phenolic acids: p-hydroxybenzoic acid, p-methoxybenzoic acid; 6 fatty acids: 1,3-di-myristic acid-2-sorbic acid-triglyceride, n-octadecanol, n-octadecanoic acid methyl ester, hexadecane Acid, eleven alkanic acid, adipic acid.
Chemical constituents of nettle
Compounds isolated and identified from 95% ethanol extract of the aerial part of Urtica angustifolia were white wax lactone, scopolamine, n-butyl-beta-D-fructofuran, trans-4-hydroxy-cinnamic acid, 5-hydroxymethyl furfural, beta-sitosterol, carotene, benzoic acid and erythritol.
1. anti rheumatic arthritis
urtica extract can alleviate the swelling degree and arthritis index of primary and secondary plantar in rats. The results showed that the high concentration water extract of Urtica broadleaf had the strongest inhibitory effect on rheumatoid arthritis in rats, which was superior to the positive drug (Tripterygium wilfordii).
2. hypoglycemic effect
urtica extract was used to treat streptozotocin-induced diabetic rats. The dosage was 100 mg Histopathological examination of diabetic rats returned to normal.
3. effect on cardiovascular disease
Nettle extract has a certain effect on cardiovascular, especially vasodilatation. Urtica decoction can obviously prolong the coagulation time and bleeding time of mice, and has obvious anticoagulation effect, suggesting that Urtica has the effect of promoting blood circulation, relieving pain and anti-thrombosis.
4. anti benign prostatic hyperplasia (BPH)
urtica extract has a strong inhibitory effect on benign prostatic hyperplasia. In foreign countries, heterotrophic urtica, eucalyptus, and Eucalyptus are used for prostatic hyperplasia, prostatitis and prostate cancer. In foreign clinical trials, the combination of heterotrophic urticaria root extract and sawn palm fruit extract can obviously improve the symptoms of prostate hyperplasia.
5. other functions
urtica extract can also be used as a herbal medicine as a diuretic, astringent, hemostatic agent and so on. Urtica has antioxidant, anti-aging, anti-microbial, anti-ulcer and other effects, can be used for beauty and health care.
Certification of Analysis
Produce Name:urtica extract
Batch Number: ALD170920 Analysis Date:2017-09-20
Manufaccture Date:2017-09-20 Expiry Date:2019-09-19
Batch Quantity: 100Kg Used Part:Leaf
Items |
Standards |
Results |
Method |
|
Physical and chemical analysis: |
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Description |
purple Powder |
Qualified |
Visual |
|
Taste&Odor |
Characteristic |
Qualified |
Organoleptic |
|
Extract Solvent |
Ethanol/water |
Qualified |
/ |
|
Assay |
50:1 |
Qualified |
HPLC |
|
Identification |
|
|
TLC |
|
Ash Content |
≤5.0% |
Qualified |
CP2015 |
|
Loss on Drying |
≤5.0% |
Qualified |
CP2015 |
|
Mesh Size |
100% pass 80 mesh |
Qualified |
CP2015 |
|
Bulk Density |
40~60g/100ml |
Qualified |
CP2015 |
|
Tap Density |
60~90g/100ml |
Qualified |
CP2015 |
|
Residue analysis: |
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Heavy Metal |
≤10ppm |
Qualified |
CP2015 |
|
Pb |
≤2.0ppm |
Qualified |
GB/T5009.12-2003 |
|
As |
≤1.0ppm |
Qualified |
GB/T5009.11-2003 |
|
Hg |
≤0.1ppm |
Qualified |
GB/T5009.17-2003 |
|
Cd |
≤1.0ppm |
Qualified |
GB/T5009.15-2003 |
|
Solvents Residue |
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Ethanol |
≤200ppm |
Qualified |
Eur.Ph 7.0<2.4.24> |
|
Pesticides Residue |
||||
Hexachlorobiphenyl |
≤0.2ppm |
Qualified |
CP2015 |
|
Dichlorodiphenyltrichloroethane (DDT) |
≤0.2ppm |
Qualified |
CP2015 |
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