Thermostable Superoxide Dismutase,SOD has that characteristic of good heat resistance, high stability, long half-life, high bioavailability, no need of modification and the like. Superoxide dismutase (SOD) is a kind of antioxidant metalloenzyme in organism, which is an important component of antioxidant enzyme system in biological system and widely distributed in microorganisms, plants and animals.
Superoxide dismutase can scavenge superoxide anion free radical (O2-) which is harmful to the body, and has the function of anti-oxidation and anti-aging. Superoxide dismutase (SOD) is a promising new enzyme with unique efficacy in the treatment of diseases caused by superoxide free radicals (O2-), such as oxygen poisoning, acute inflammation and senile cataract. It can catalyze the dismutation of superoxide anion free radicals to oxygen and hydrogen peroxide, which plays a vital role in the balance of oxidation and antioxidant in the body, and is being studied as an anti-aging product.As a scavenger of superoxide anion radical, SOD is widely used in delaying human aging, improving human immunity, and as an additive in food and cosmetics.
Application.
(1) Anti-oxidation and anti-aging.
SOD can remove and reduce excessive free radicals in human body and delay aging. It can continuously remove the oxygen free radicals produced by excessive oxygen consumption of melanin under light, and prevent the formation of excessive melanin. At the same time, it can also continuously remove oxygen free radicals produced by lipofuscin and waxy matter to avoid excessive lipid peroxidation, reduce the formation of lipofuscin and waxy matter, and then play a role in preventing aging.
Anti-inflammatory. SOD has a strong anti-inflammatory effect, which can be used to inhibit inflammation by its antioxidant effect, and has a good application prospect in the treatment of inflammation.
(2) Food industry.
SOD is added to food as a natural antioxidant and can be used as a preservative. SODs are processed into health products and food additives in various forms for use, such as SOD-added milk, beer, soft candy and other types of food nutrition enhancers. The oral administration of SOD is effective and can be absorbed into the human body through the gastrointestinal tract, so SOD chewing gum, SOD lozenge and oral liquid have emerged one after another and become one of the important ways to supplement SOD in vitro.
(3) Daily chemical industry.
The main applications of SOD in daily chemical industry are skin care products and toothpaste. The supplement of exogenous SOD is beneficial to delaying skin aging, resisting oxidation and removing color spots. Therefore, many cosmetic manufacturers at home and abroad have added a certain proportion of SOD into their products.
SOD has the following functions in skin care products: First, as a cosmetic additive, it can prevent skin aging, reduce wrinkles and remove freckles, and has the effect of skin care; Second, it can prevent and treat related skin diseases, such as acne, skin burns and so on. . SOD has anti-inflammatory effect, is purely natural and has no toxic or side effects, so it plays an important role in oral and dental health care, such as toothpaste, mouthwash, chewing gum and so on.
(4) Agriculture.
By means of genetic engineering, increasing the expression of SOD in plants can greatly enhance the stress resistance of plants. For example, the overexpression of Fe-sod SODcould enhance the resistance of chloroplast plasma membrane and photosynthetic system II to MV MV MV (methyl viologen) and high salt peroxidation stress.