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Immune System

AHCC may help boost immunity, according to one small clinical trial in Nutrition and Cancer.For the study, 21 healthy volunteers took either an AHCC supplement or a placebo every day for four weeks. At the study's end, members of the AHCC group showed a significantly greater increase in the number of dendritic cells—a type of cell involved in the immune response.

Chemotherapy Side Effects

Animal-based research shows that AHCC may help reduce certain side effects of chemotherapy. For instance, in a 2009 report from the Journal of Experimental Therapeutics and Oncology, scientists discovered that treating mice with AHCC helped shield them from chemotherapy-induced liver damage and bone marrow suppression.

Cancer

AHCC may help inhibit cancer development. A 2018 study published in Nutrition and Cancer found that AHCC inhibits the proliferation of ovarian cancer cells.3 Researchers suggest that the compound has potential for use as complementary cancer therapy for ovarian cancer. The compound may have the potential for therapeutic use in the treatment of other cancers as well.

Inflammatory Bowel Disease

AHCC shows promise in the treatment of inflammatory bowel disease. A 2014 study found that AHCC had therapeutic effects on lymphocyte driven colitis in mice. The researchers suggest that these findings indicate that AHCC may have beneficial anti-inflammatory effects in the relief of inflammatory bowel disease.

Flu

In tests on mice, scientists have demonstrated that AHCC may help rev up the immune response to flu infection. For example, in a 2009 study from the Nutrition Research, AHCC appeared to reduce the severity of flu infection and boost activity in natural killer cells (a major player in immune response) in influenza-infected mice.