Blood Grouping Reagent Anti Monoclonal Diagnostic Test Kit

BLOOD GROUP 3x10 ML (ABD)

Intended Use:

Test for qualitative detection of ABO antigens on human RBCs by immunoagglutination method.

Introduction:

The mouse monoclonal IgM Anti-A, Anti-B and Anti-AB antibodies are produced “in-vitro” as culture supernatant of selected hybridoma, obtained by the fusion of mouse antibody producing B-lymphocytes with mouse myeloma cells. Monoclonal sera ANTI-A, ANTI-B and ANTI-AB are specific IgM immunoglobulin which are directed against the human red blood cell antigens A, B and AB respectively. Monoclonal sera immunoglobulins are produced from individual cell line hence they are identical in their chemical structure and biological activity. The Rho (D) antigen is found on erythrocytes of approximately 95% of the Indian population. The terms “Rh” positive or “Rh” negative are understood to refer solely to the presence or absence of this antigen accordingly. Anti D (Rho) monoclonal IgM is used for the detection of the presence of Rho antigen on the red blood cells.

Method Principle:

Human red cells possessing A and/or B blood group antigen will be agglutinated by monoclonal sera directed towards the respective antigen (s), indicating positive test. Absence of agglutination cells with Anti-A, Anti-B and Anti-AB reagents is a negative test results and indicates the absence of the corresponding antigen.Human red cells possessing Rho D antigen will be agglutinated by monoclonal sera directed towards the respective antigen (s), indicating positive test. Absence of agglutination cells with ANTI-D (IgM), ANTI-D (IgG + IgM), Anti - D (IgG), Anti D (Rho IgG + IgM) reagents is a negative test results and indicates the absence of the corresponding antigen.

BLOOD GROUP 4x10 ML (ABD AB)

Intended Use:

Test for qualitative detection of ABO antigens on human RBCs by immunoagglutination method.

Introduction:

The mouse monoclonal IgM Anti-A, Anti-B and Anti-AB antibodies are produced “in-vitro” as culture supernatant of selected hybridoma, obtained by the fusion of mouse antibody producing B-lymphocytes with mouse myeloma cells. Monoclonal sera ANTI-A, ANTI-B and ANTI-AB are specific IgM immunoglobulin which are directed against the human red blood cell antigens A, B and AB respectively. Monoclonal sera immunoglobulins are produced from individual cell line hence they are identical in their chemical structure and biological activity. The Rho (D) antigen is found on erythrocytes of approximately 95% of the Indian population. The terms “Rh” positive or “Rh” negative are understood to refer solely to the presence or absence of this antigen accordingly. Anti D (Rho) monoclonal IgM is used for the detection of the presence of Rho antigen on the red blood cells.

Method Principle:

Human red cells possessing A and/or B blood group antigen will be agglutinated by monoclonal sera directed towards the respective antigen (s), indicating positive test. Absence of agglutination cells with Anti-A, Anti-B and Anti-AB reagents is a negative test results and indicates the absence of the corresponding antigen.Human red cells possessing Rho D antigen will be agglutinated by monoclonal sera directed towards the respective antigen (s), indicating positive test. Absence of agglutination cells with ANTI-D (IgM), ANTI-D (IgG + IgM), Anti - D (IgG), Anti D (Rho IgG + IgM) reagents is a negative test results and indicates the absence of the corresponding antigen.

Pack Size:

3x10 ML

Pack Size:

4x10 ML.

Dispatch time in weeks:

2 to 4 weeks.